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LP

Songcatcher January 28, 2011 February 22, 2011

Forums

Not sure if this has been anounced on here or not, but I lifted this anouncement from the LB forum. Exciting news for Appaloosa breeders. [quote]A new DNA test will be available soon for Appaloosa or leopard-complex coat pattern. A disorder known as congenital stationary night blindness (CSNB) a condition making it difficult or impossible to see in relatively low light has been directly linked to the leopard complex in Appaloosa horses. DNA test for the LP mutations can also provide clear information as to CSNB. Thanks and Please contact Animal Genetics for additional information coming soon. [/quote]

Third Peppermint Fri, 01/28/2011 - 14:33

That is AWESOME! Yay! :)

Daylene Alford Fri, 01/28/2011 - 14:36

Awesome! Been waiting for this for a long time.

critterkeeper Sun, 01/30/2011 - 14:25

Wow that is great news for all the LP lovers.... I always thought there was one mutation (LP or lp), but this information seems to indicate that it is a combination of 3 mutations producing a single result (spotted or not)...or am I misinturpreting the data (not unheard of ymwhisle ). Either way kinda kewl from a genetics stand point. :toast

accphotography Sun, 01/30/2011 - 14:30

No there's just one mutation, LP (lp is wild type). They are just saying they essentially found three "markers" that go along with LP close enough to do a haplotype test. It's just like the dun test if I'm reading right.

critterkeeper Tue, 02/01/2011 - 17:23

Thanks Audrey for clearing that up for me....sometimes my mind just can't wrap itself around problems like it used to (dang grey hair, it does strange and fuzzy things to the brain... :BH ) ymwhisle

CheyAut Fri, 02/11/2011 - 15:02

"Dear Members,

Given that so many of you have posted questions about a DNA test for LP and CSNB, I wanted to share this exciting news with you. We have recently identified the causative mutation for LP and CSNB. We are currently preparing the manuscript for publication. Once the discovery has been published, I will send an update with all of the details and of course answer any questions you might have. In the meantime, we are working with Cornell University to patent the discovery. When a license has been purchased by a commercial laboratory (to offer the DNA test for the causative mutation) I will let you know. Thank you to everyone that has contributed to the thousands of samples, over the past thirteen years, that has made all of this research possible.
Sincerely,
Rebecca Bellone, Ph.D."

CheyAut Thu, 04/28/2011 - 07:51

[quote=accphotography]No there's just one mutation, LP (lp is wild type). They are just saying they essentially found three "markers" that go along with LP close enough to do a haplotype test. It's just like the dun test if I'm reading right.[/quote]

They have now isolated the gene responsible, so it will be like the extension test :)