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Lavender Foal Syndrome

Daylene Alford January 12, 2010 February 22, 2011

Forums

I'd like to find some more information on this. Does anyone have any links or pictures handy? Thanks, Daylene

horsegen Tue, 01/12/2010 - 15:36

Samantha Brooks is doing the research on this at Cornell. The last I heard, which was last May, they had identified the gene and the mutation. I'm sure a publication is in the works. I don't have any good references on it, but that's the news from a genetics standpoint.

Maigray Tue, 01/12/2010 - 16:47

A google search on the term will give you most of the pertinent info, including pics. There is a fair amount of information on most of the Arabian horse forum boards, but you will have to do a search to find the relevant posts. Ablackhorse is open for this, I believe. It's pretty straightforward - genetic lethal disorder, recessive, present in certain Arabian horse populations. Affected foals present with an obvious neurological disorder, they wont' ever get up and will be euthanized. They have a funny coat color - that's where it got its name. I've seen it in pictures and if you're familiar with color expression, you'll immediately notice it.

RiddleMeThis Tue, 01/12/2010 - 17:47

According to an article that I just read while looking for pictures a lab in South Africa has found the mutation and is offering a test for it as well.

Im on my phone so I can't copy a link but a quick google should bring it up

Daylene Alford Fri, 01/15/2010 - 06:05

That is awesome that they have a test. I'm thinking maybe I should right something up about this in the dilution section? It does after all appear to dilute the coat color.

Maigray Fri, 01/15/2010 - 12:30

I think it's cool to mention it -but I would emphasize the color is not the reason for the disease because I have had people question me about that, asking if the color was what was causing it, instead of the other way 'round. But in that case, should we write up something about the ASD gene in the Silver section? And the effects of grey on melanomas + agouti, etc. and etc. I've actually been thinking about it for a while.

accphotography Fri, 01/15/2010 - 12:47

I think we should Mai. Maybe make a single page and list all of these conditions then when it's mentioned in a color page you can just link them to the disease page for more info or something.

Jenks Fri, 01/15/2010 - 14:12

Well the cause of the color is open and hollow hair shafts in varying degrees. A lot of horses have hollow hair shafts, so.... The lightening effect is because the end of the shaft is open, which I would think would be very dry and brittle very quickly, so I don't think it would be a cool thing to have even minus the horrid other effect.

Ridiculous to think anyone could think a [i]color[/i] could cause anything but color, but you are right. Grey's DO have more melanomas, etc. I think a lot of people have an aversion to white for a similar reason.

Dogrose Fri, 01/15/2010 - 14:43

Rats have a colour called topaz in the UK, fawn in the US, which also have platelet pool deficiency and seratonin uptake problems. There are similar mutations in humans which cause the same physiological problems and a type of albinism, and loads in mice!
There is a table on this page with a huge list of physiological abnormalities and their associated affects on pigmentation in mice.
http://www.espcr.org/micemut/" onclick="window.open(this.href);return false;

Monsterpony Fri, 01/15/2010 - 16:31

I can right up a page on the genetic condition linked to coat colors as I am in the process of writing up my senior thesis on it.

Jenks Fri, 01/15/2010 - 18:47

[quote="Monsterpony"]I can right up a page on the genetic condition linked to coat colors as I am in the process of writing up my senior thesis on it.[/quote]

How awesome! I cannot wait to read it.