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Brindling only on one side?

Would there be a genetic reason why a horse would have brindling only on one side? I couldn't think of one...but I always have trouble figuring these things out.

lipigirl Mon, 06/14/2010 - 11:20

If it were a chimera then I don't see why it couldn't be just down one side - otherwise I have no idea but Chimera makes sense.

Gander Mon, 06/14/2010 - 12:01

OK...so 'chimera' is when there's an extra DNA code, yes? The horse in question is a registered Thoroughbred, so would that generally exclude a chimeric horse? (since they probably wouldn't register such a horse) Or could a TB be chimeric, and registered? (I know...weird question, ha ha)

I feel like there was a case with some brindle horse (an offspring of Sharp One, perhaps?), where her DNA tests showed some abnormality, and the registry questioned it. ?

Thanks for your thoughts!!

lipigirl Mon, 06/14/2010 - 16:16

They may well not be aware this TB is a Chimera, as it is 2 embryos fusing in the womb. off topic was just looking though your book today if you want to come to little old England and take pics we'd love to see you. ;-)

Gander Mon, 06/14/2010 - 17:45

lipigirl, Thanks for your note! (and, how much would I LOVE come visit little old England....*sigh*...it's #1 on my hit list) (I must find a benefactor, ha ha!!)

OK, here's where my lack of knowledge comes into play. So, the 2 embryos fusing in the womb thing...you'd think I'd understand that part. But then I read this article, and it sounds as if such chimerism will always result in "extra"/confusing DNA. ?

http://americashorsedaily.com/one-in-a-…" onclick="window.open(this.href);return false;

This article/concept makes me think a TB couldn't be chimeric and be easily registered. But, otherwise, it certainly would explain stripes on one side and not the other. (?)

Thanks again! :)

RiddleMeThis Mon, 06/14/2010 - 17:53

I don't see how a chimeric TB COULDN'T be registered as long as he was conceived by live cover. Does the jockey club not allow registration of twins?

Daylene Alford Mon, 06/14/2010 - 17:57

A chimera has the DNA of two different horses. So in a way they do have "extra" DNA. When the embryos fuse it is very early in development so each embryo forms different parts of the horse (or other animal). This is what causes the stripes. If you take DNA samples from different color stripes they will test as being different animals.

Daylene Alford Mon, 06/14/2010 - 17:58

In fact with Dunbars Gold one embryo was male and one was female. His genitals just happened to be formed by the male embryo.

Gander Mon, 06/14/2010 - 18:23

[quote="RiddleMeThis"]I don't see how a chimeric TB COULDN'T be registered as long as he was conceived by live cover. Does the jockey club not allow registration of twins?[/quote]

Yep, they do. I just thought that if the DNA of a foal raised any flags, the Jockey Club would have never even heard of chimeras (let alone understood how such a thing can affect DNA). They are very, very particular/careful. I just don't see the Jockey Club saying, "Wow, that DNA on this critter is really odd...but it's simply a chimera, so it's OK."

But in reading the posted article carefully, and adding in what admin wrote about the stripes.... On a chimera, does the blood test come up clear and cleanly as one mare/one stallion, and it's only the hair samples that might cause issues? In that case, I could see the Jockey Club being happy with the blood test.

(I'll quit asking soon, ha ha, so no one's head pops off trying to explain it) :hammer :-D

Thanks again!

Monsterpony Mon, 06/14/2010 - 20:30

Since both of the embryos were produced by the same sire/dam, then they wouldn't even be able to tell when doing the parentage verification as either embyro would test appropriately. They would only run into a problem if someone was registering a colt and the DNA sample they received was from a female (or vice versa).

NZ Appaloosas Tue, 06/15/2010 - 02:04

which is how the chimerism in one QH was "discovered" (at least that was the impression on the article I read some while back)...foal was being PV'd, dam and sire samples sent in, and lab wrote back saying sorry, don't need two mare samples, need sire and dam sample, stallion owners said "uh, we did send sire sample", and lab said can't have, the two samples are both genetically female.

Must have been a 'fun' conversation!

Diane

Dogrose Tue, 06/15/2010 - 03:52

There was a male tortoiseshell point siamese cat registered in the UK some time ago who was tortoiseshell on one side of his body and plain seal point on the other. He had one orange t esticle and one seal one. He was fertile but bred as a seal point.
Edited because I wasn't allowed to use the 't' word, bit odd on a genetics site :roll:

Daylene Alford Tue, 06/15/2010 - 08:33

I thought I had all the anatomical terms removed from the filter list but had missed testicle. You can now say testicle =)

Gander Sat, 06/26/2010 - 22:21

[quote="admin"]A chimera has the DNA of two different horses.... If you take DNA samples from different color stripes they will test as being different animals.[/quote]

Sorry to revisit this (I've been traveling) ;), but.... If it's a chimeric brindle, with white stripes on a bay coat, will the white stripes and bay coat reflect the DNA of two different animals, [i]every single time?[/i]

Thanks!!!!! I just want to be certain as I'm writing something for an article - hate to mess up things in print! :)

accphotography Sat, 06/26/2010 - 22:28

If they are chimeric, that is the theory, yes. There may be hard core evidence to that but I'm not sure where to find it.

Gander Sat, 06/26/2010 - 22:40

Thanks, ACC! :) Such a shame that so many things along these lines are in theory, not necessarily provable fact (at least not fact that I can find, ha ha). I thought the Dunbar's Gold/Sharp One's offspring article might confirm the two colored stripes/two DNA things, but it doesn't seem to mention it being a certainty.

By the way, off-topic, but those photos of the True Colours' horses are GREAT!!!!!!!!!

accphotography Sat, 06/26/2010 - 23:36

Well the thing that throws us is that horses like Natal Clasi don't test to be chimeric... so apparently the color of the stripes doesn't tell us if they're chimeric or otherwise. It's odd. Based on this girl's presentation (only partially brindled) I'd say it's more likely she's chimeric.

Oh shoot I have a quote to get to you don't I? Eeeks.

Your topic. :rofl: Thanks a bunch! :oops: Still kicking myself that the light got the best of me on a couple of the horses though. :evil:

Gander Sat, 06/26/2010 - 23:56

Now you got me...ha ha.... I can't think of what quote you have to get me! ;) Duh.... (it's late) ;) ;)

Thanks for the info! I'll just use generalities on some of this stuff as I can't stand being wrong in articles - ugh!

So...hmmm....the light got the best of you on some of those horses, hmm? You hide that well! Looks like you got the best of the light and the horses!

Thanks again!

accphotography Sun, 06/27/2010 - 00:45

Hahaha! Yeah something about no new brindles or something. I need to read the email again.

Oh yeah... take a look at a couple of the Iris photos and you'll see what I mean. They're the worst thankfully. You flatter me. Tisk tisk. :D